ЗНЕБОЛЕННЯ ЯК ФАКТОР ПОКРАЩЕННЯ ЯКОСТІ ЖИТТЯ ПАЛІАТИВНИХ ПАЦІЄНТІВ
DOI:
https://doi.org/10.32782/2226-2008-2024-5-10Ключові слова:
паліативна та хоспісна допомога, основний паліативний діагноз, реімбурсація, огляд літературиАнотація
Паліативна та хоспісна допомога (ПХД) надається хворим з невиліковними захворюваннями для покращення якості їхнього життя та зменшення страждань. Дослідження проведене з метою вивчення питань хронічного болю у паліативних хворих, адекватного знеболення залежно від основного паліативного захворювання. Огляд літературних джерел та нормативно-правових актів України показав недосконалість практики організації знеболення паліативних хворих в Україні порівняно з практикою країн із розвиненими системами ПХД. Препарати для знеболення лише частково підлягають реімбурсації. Оцінити результати організації знеболення дозволяють стандартні та модифіковані опитувальники про якість життя SF-36. Для покращення організації знеболення необхідні перегляд переліку паліативних діагнозів, подальша розбудова системи ПХД у межах реформи всієї системи охорони здоров’я.
Посилання
WHO methods and data sources for global burden of disease estimates 2000–2019. Geneva: WHO; 2020. 47 p. Available from: https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2019_daly-methods.pdf.
Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012; 380(9859): 2163–96. doi: 10.1016/S0140-6736(12)61729-2.
Serdiuk AM, Kartashova SS. Lost years of potential life in the population of Ukraine as an indicator for the determination of health care priority tasks. Environment & Health. 2019; (3): 4–10. doi: 10.32402/dovkil2019.03.004 (in Ukrainian).
Holovanova IA, Shevchenko AS. Determination of the main needs of palliative patients and ways of their provision in the healthcare system of Ukraine. Experimental and Clinical Medicine. 2021; 90(3): 88–94. doi: 10.35339/ekm.2021.90.3.hos.
Nair K, Lee M, Hobson E, Oliver D, Husbands E. End-of-life care of people with long-term neurological conditions. Pract Neurol. 2022; 22(5): 385–91. doi: 10.1136/practneurol-2022-003361.
Lekhan VM. The importance of medical cannabis for solving the problem of providing analgesia to palliative patients in Ukraine. Experimental and Clinical Medicine. 2024; 93(1): 87–93. doi: 10.35339/ekm.2024.93.1.lvm.
Nesterenko VG. The controllability of pain in palliative medicine as a factor in the medical and social impact on the patients’ quality of life at the end-of-life. Experimental and Clinical Medicine. 2024; 93(1): 69–86. doi: 10.35339/ekm.2024.93.1.nes (in Ukrainian).
Holovanova IA, Shevchenko AS. Evaluation of packaged funding programs for palliative and hospice care by the National Health Service of Ukraine. Experimental and Clinical Medicine. 2021; 90(4): 45–52. doi: 10.35339/ekm.2021.90.4.hos.
Holovanova IA, Shevchenko AS. The issue of patient-oriented organization of palliative and hospice care in Ukraine. Experimental and Clinical Medicine. 2021; 90(2): 21–7. doi: 10.35339/ekm.2021.90.2.hos.
Lekhan VM. Retrospective analysis of the construction of the national system of hospice and palliative care in Great Britain. Inter Collegas. 2024; 11(1): 52–56. doi: 10.35339/ic.11.1.lvm.
Nesterenko VG. The need for palliative and hospice care in Ukraine in 2018–2020. Medicine Today and Tomorrow. 2021; 90(3): 43–52. doi: 10.35339/msz.2021.90.3.nes (in Ukrainian).
Nesterenko VG. Forecasting the need for palliative and hospice care in Ukraine for 2021–2022. Experimental and Clinical Medicine. 2021; 90(4): 25–34. doi: 10.35339/ekm.2021.90.4.nes (in Ukrainian).
Nesterenko VG, Redka IV, Sukhonosov RO, Grygorov SM, Shevchenko AS, Aliieva TD. Forecasting the need for palliative and hospice care using the creeping trend method with segment smoothing. Wiad Lek. 2024; 77(5): 980–4. doi: 10.36740/WLek202405116. PMID: 39008586.
Lekhan VM. Impact of different types of pain on organizational decisions in palliative medicine. Medicine Today and Tomorrow. 2024; 93(1): 47–55. doi: 10.35339/msz.2024.93.1.lvm.
Cimino V, Chisari CG, Toscano S, Patti F. Palliative care in multiple sclerosis. Handb Clin Neurol. 2023; 191: 129–38. doi: 10.1016/B978-0-12-824535-4.00009-4.
Laboratory of System Analysis. Stages of system analysis according to E.P. Golubkov. 2024. doi: 10.5281/zenodo.10645560 (in Ukrainian).
Order of the Ministry of Health of Ukraine No. 1308 on 04 June 2020 “On improving the organization of palliative care in Ukraine”. Valid on 21 July 2024. Verkhovna Rada (Parliament) of Ukraine. Legislation of Ukraine. (In Ukrainian). Available from: https://zakon.rada.gov.ua/laws/show/z0609-20.
National Health Service of Ukraine. Contracting (2021–2025) [Internet]. (In Ukrainian). Available from: https://contracting.nszu.gov.ua/kontraktuvannya (Last accessed: 21 July 2024).
Inpatient palliative medical care for adults and children. In: Guide “Packages of medical services: content and approach to contracting of health care institutions”. Requirements for service packages of the medical guarantee program. Kyiv: National Health Service of Ukraine; 2021. P. 182–90. (In Ukrainian). Available from: https://contracting.nszu.gov.ua/storage/editor/files/pmg-booklet-2303.pdf.
Specifications and conditions of procurement under the medical guarantee program in 2022. National Health Service of Ukraine. [Internet]. Available from: https://contracting.nszu.gov.ua/kontraktuvannya/kontraktuvannya-2022/vimogipmg-2022 (Last accessed: 21 July 2024).
Vearrier D, Grundmann O. Clinical Pharmacology, Toxicity, and Abuse Potential of Opioids. J Clin Pharmacol. 2021;61 Suppl 2: S70–S88. doi: 10.1002/jcph.1923.
Stein C. Opioid analgesia: recent developments. Curr Opin Support Palliat Care. 2020; 14(2): 112–7. doi: 10.1097/SPC.0000000000000495.
Sivanesan E, Gitlin MC, Candiotti KA. Opioid-induced Hallucinations: A Review of the Literature, Pathophysiology, Diagnosis, and Treatment. Anesth Analg. 2016; 123(4): 836–43. doi: 10.1213/ANE.0000000000001417.
Ustinov OV. The Ministry of Health checks the intended use of funds under the Medical Guarantee Program. Ukrainian Medical Journal. 2023 [Internet]. (In Ukrainian). Available from: https://umj.com.ua/uk/novyna-247858-moz-pereviryyaetsilove-vikoristannya-koshtiv-vid-programi-medichnih-garantij (Last accessed: 23 July 2024).
Waters LM, Wright PM. Hospice Fraud: Predicting Ability and Intent. Illness, Crisis & Loss. 2024; 32(3): 461–72. doi: 10.1177/10541373241232483.
Requirements of the Medical Guarantee Program 2023. National Health Service of Ukraine [Internet]. (In Ukrainian). Available from: https://contracting.nszu.gov.ua/kontraktuvannya/kontraktuvannya-2023 (Last accessed: 22 July 2024).
Ukraine. Rapid damage and needs assessment. February 2022 – February 2023. Himmelfarb A (ed). World Bank, Government of Ukraine, European Union, United Nations; 2023. 142 p. Available from: https://documents1.worldbank.org/curated/en/099184503212328877/pdf/P1801740d1177f03c0ab180057556615497.pdf.
Calculator of the approximate amount of the contract for providers who will conclude a contract with the National Health Service for packages of specialized medical care. National Health Service of Ukraine, 2024. [Internet]. (In Ukrainian). Available from: https://contracting.nszu.gov.ua/kontraktuvannya/kontraktuvannya-2024-1699952970/calculator-03012024.
Reimbursement program for medicinal products and medicinal products. National Health Service of Ukraine, 2024. [Internet]. (In Ukrainian). Available from: https://contracting.nszu.gov.ua/ogoloshennya-pro-ukladennya-dogovoriv/dostupni-liky.
The list of medicines that are subject to reimbursement under the program of state guarantees of medical care of the population, on 12 Feb 2024. National Health Service of Ukraine. [Internet]. (In Ukrainian). Available from: https://contracting.nszu.gov.ua/storage/editor/files/doc11.pdf.
The list of medical products that are subject to reimbursement under the program of state guarantees of medical care of the population, on 12 Feb 2024. National Health Service of Ukraine. [Internet]. (In Ukrainian). Available from:
https://contracting.nszu.gov.ua/storage/editor/files/54229-dn-414-12032024-dod.pdf.
Rosenberger DC, Blechschmidt V, Timmerman H, Wolff A, Treede RD. Challenges of neuropathic pain: focus on diabetic neuropathy. J Neural Transm (Vienna). 2020; 127(4): 589–624. doi: 10.1007/s00702-020-02145-7.
Jensen TS, Karlsson P, Gylfadottir SS, et al. Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management. Brain. 2021; 144(6): 1632–45. doi: 10.1093/brain/awab079.
Standards of medical care “Chronic pain syndrome in adults and children”, approved by Order of the Ministry of Health (MH) of Ukraine No. 643 on 6 Apr 2023. State Expert Center of the MH of Ukraine. [Internet]. (In Ukrainian). Available from: https://www.dec.gov.ua/mtd/hronichnyj-bolovyj-syndrom (Last accessed: 22 Jul 2024).
Anekar AA, Hendrix JM, Cascella M. WHO Analgesic Ladder. [Updated 23 Apr 2023]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554435/.
Hubskyi YuI, Khobzei MK. Pharmacotherapy in palliative and hospice medicine. Clinical, pharmaceutical and medico-legal aspects. Kyiv: Health; 2011. 352 p. (in Ukrainian).
Mercadante S, Gregoretti C, Cortegiani A. Palliative care in intensive care units: why, where, what, who, when, how. BMC Anesthesiol. 2018; 18(1): 106. doi: 10.1186/s12871-018-0574-9. PMID: 30111299.
Pelle AJ, Kupper N, Mols F, de Jonge P. What is the use? Application of the short form (SF) questionnaires for the evaluation of treatment effects. Qual Life Res. 2013; 22(6): 1225–30. doi: 10.1007/s11136-012-0266-8.
Lins L, Carvalho FM. SF-36 total score as a single measure of health-related quality of life: Scoping review. SAGE Open Med. 2016; 4: 2050312116671725. doi: 10.1177/ 2050312116671725.
Vorobets DZ, Chaplyk VV, Besedina АS, Vorobets МZ, Onufrovych ОК, Fafula RV, Vorobets ZD. Indicators for evaluating the quality of life of men injured by the consequences of combat actions. Experimental and Clinical Medicine. 2023; 92(4): 87–94. doi: 10.35339/ekm.2023.92.4.vsb (in Ukrainian).
Campolina AG, Ciconelli RM. SF-36 and the development of new assessment tools for quality of life. Acta Reumatol Port. 2008; 33(2): 127–33. PMID: 18604180.
Nesterenko VG. Peculiarities of using the SF-36 questionnaire in palliative neurological patients. Medicine Today and Tomorrow. 2023; 92(2): 62–72. doi: 10.35339/msz.2023.92.2.nes (in Ukrainian).
Nesterenko VG. Peculiarities of using the SF-36 questionnaire in palliative oncological patients. Experimental and Clinical Medicine. 2023; 92(3): 73–85. doi: 10.35339/ekm.2023.92.3.nes (in Ukrainian).
Demuro M, Bratzu E, Lorrai S, Preti A. Quality of Life in Palliative Care: A Systematic Meta-Review of Reviews and Meta-Analyses. Clin Pract Epidemiol Ment Health. 2024; 20: eІ7450179183857. doi: 10.2174/0117450179183857240226094258.
Thaniyath TA. The Quality of Life of the Patients Under Palliative Care: The Features of Appropriate Assessment Tools and the Impact of Early Integration of Palliative Care. Chapter in: IntechOpen; 2019. 13 p. doi: 10.5772/intechopen.85161.
Nesterenko VH, Peresypkina TV, Shevchenko OS, Sarkhadova II. Palliative and hospice care in the Kharkiv region in the first year of the war. Ukraine. Nation’s Health. 2023; 73(3): 106–12. doi: 10.32782/2077-6594/2023.3/18.