PATHOGENETIC PREREQUISITES FOR EARLY PREGNANCY LOSS
DOI:
https://doi.org/10.32782/2226-2008-2023-3-13Keywords:
early pregnancy loss, inflammatory diseases, immune system disorders, antiphospholipid syndromeAbstract
Early pregnancy loss is one of the most pressing problems today, as there is no single cause and simple methods of prevention. As a rule, placental dysfunction is formed against the background of problems associated with primary infection of the endometrium, progesterone deficiency, features of the local immune response to pregnancy. Placental dysfunction can, in turn, result in premature spontaneous termination in the early and late stages, premature detachment of the normally and low- situated placenta, stillbirths and preterm births with or without Massive Obstetric haemorrhage. Such complications pose a serious threat to the lives of not only the child but also the mother, requiring doctors to make every effort to save lives and save the families who have appeared in such situation. In this article we open the most common and often faced problems in carrying the baby. The first part of the article enlighten the specific details and effect of inflammatory process in relation to women’s past sexual history and the agents causing history and the agents causing the process of following chronic endometritis. The result of the long lasting chronic disease in endometrium and endomyometrium as well as first pregnancy termination leads to placental insufficiency appearance. The second part lights the hemodynamic disorders at women’s body which leads to miscarriages. The main problem in that case are clots in vessels which could be the manifestation of the AFL syndrome which contributes to the poor obstetric history and multiply miscarriages. The third part deals with local and general immune status which condition and role is not less than any other in successful pregnancy course.
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