MAGNETIC RESONANCE NANOTHERANOSTICS OF MALIGNANT TUMORS
Keywords:
malignant tumors, nanotheranostics, magnetic nanocomplex, magnetic resonance imaging, electromagnetic radiationAbstract
Medical physical principles of magnetic resonance nanotheranostics of malignant tumors during magnetic resonance imaging, magnetic nanohyperthermia and magnetic nanotherapy at temperatures up to 40°C are described. The results of experimental and clinical studies discussed in the paper indicate about future prospects of cancer nanotheranostics.
References
The bio-energetic theory of carcinogenesis / M. J. Gonzalez, J. R. M. Massari, J. Duconge [et al.] // Medical Hypotheses. – 2012. – Vol. 79. – P. 433–439.
Szent-Györgyi A. Bioelectronics and cancer / A. Szent-Györgyi // Journal of Bioenergetics and Biomembrane. – 1973. – Vol. 4, N 6. – P. 533–562.
Multi-modal strategies for overcoming tumor drug resistance: hypoxia, the Warburg effect, stem cells, and multifunctional nanotechnology / L. Milane, S. Ganesh, S. Shah [et al.] // Journal of Controlled Release. – 2011. – Vol. 155, N 2. – P. 237–247.
Hughes M. P. Nanoelectromechanics in engineering and biology / M. P. Hughes. – Boca Raton : CRC Press, 2003. – 344 p.
Magnetic nanoparticles in cancer theranostics / O. L. Gobbo, K. Sjaastad, M. W. Radomski [et al.] // Theranostics. – 2015. – Vol. 5, N 11. – P. 1249–1263.
Thomas R. Magnetic iron oxide nanoparticles for multimodal imaging and therapy of cancer / R. Thomas, I.-K. Park, Y.-Y. Jeong // International Journal of Molecular Sciences. – 2013. – Vol. 14. – P. 15910–15930.
Sprawls P. Magnetic resonance imaging principles, methods, and techniques [Електронний ресурс] / P. Sprawls. – 2009. – Режим доступу : http://www.sprawls.org/mripmt/index.html
Хорнак Д. П. Основы МРТ / Д. П. Хорнак ; пер. с англ. И. Н. Гиппа. – Рочестер : Технологический институт Рочестера, Центр визуализирующих методов, 2003.
Magnetic fluid hyperthermia (MFH): Cancer treatment with AC magnetic field induced excitation of biocompatible superparamagnetic nanoparticles / A. Jordan, R. Scholz, P. Wust [et al.] // Journal of Magnetism and Magnetic Materials. – 1999. – Vol. 201, N 1/3. – P. 413–419.
Barnes F. S. The effects of weak magnetic fields on radical pairs / F. S. Barnes, B. Greenebaum // Bioelectromagnetics. – 2015. – Vol. 36, N 1. – P. 45–54.
Preparation of magnetic polybutylcyanoacrylate nanospheres encapsulated with aclacinomycin A and its effect on gastric tumor / H. Gao, J.-Y. Wang, X.-Z. Shen [et al.] // World Journal of Gastroenterology. – 2004. – Vol. 15, N 14. – Р. 2010– 2013.
Gutman E. M. Mechanochemistry of materials / E. M. Gutman. – Cambridge : Int Science Publishing, 1998. – 212 p.
Kuramitz H. Magnetic microbead-based electrochemical immunoassays / H. Kuramitz // Analytical and Bioanalytical Chemistry. – 2009. – Vol. 394, N 1. – P. 61–69.
Магнитные конфигурации в области наноконтакта между ферромагнитными «берегами» / Л. Л. Савченко, А. К. Звездин, А. Ф. Попков, К. А. Звездин // Физика твердого тела. – 2001. – Т. 43, № 8. – C. 1449–1454.
Investigation of nonlinear magnetic properties magnetomechano-chemically synthesized nanocomplex from magnetite and antitumor antibiotic doxorubicin / V. E. Orel, A. D. Shevchenko, A. Y. Rykhalskiy [et al.] // Physics: Nanocomposites, Nanophotonics, Nanobiotechnology, and Applications. – Vol. 156 ; eds. O. Fesenko, L. Yatsenko. – Switzerland : Springer Proceedings in Physics. – 2015. – Ch. 8. – P. 103–110.
Косевич А. М. Нелинейные волны намагниченности. Динамические и топологические солитоны / А. М. Косевич, Б. А. Иванов, А. С. Ковалев. – К. : Наукова думка, 1988. – 304 с.
Stoll R. L. The analysis of eddy currents / R. L. Stoll. – Oxford : Oxford University Press, 1974. – 128 p.
Fert A. The origin, development and future of spintronics / A. Fert // Physics-Uspekhi. – 2008. – Vol. 178, N 12. – P. 1336–1348.
Use of magnetic resonance targeting to steer ov-loaded cell-based therapies to tumor sites in vivo / M. Muthana, A. Kennerley, E. Murphy [et al.] // Journal for ImmunoTherapy of Cancer. – 2015. – Vol. 3. – Suppl. 2. – P. 339.
Medical applications of iron oxide nanoparticles / A. K. A. Silva, A. Espinosa, J. Kolosnjaj-Tabi [et al.] // Iron oxides: from nature to applications ; ed. D. Faivre. – Wiley-VCH Verlag GmbH & Co. KGaA, 2016. – P. 423–471.
Local arterial infusion of superparamagnetic iron oxide particles in hepatocellular Carcinoma: A Feasibility and 3.0 T MRI Study / O. Dudeck, K. Bogusiewicz, J. Pinkernelle [et al.] // Investigative Radiology. – 2006. – Vol. 41, N 6. – P. 527–535.
Electromagnetic heating of breast tumors in interventional radiology: in vitro and in vivo studies in human cadavers and mice / I. Hilger, W. Andrä, R. Hergt [et al.] // Radiology. – 2001. – Vol. 218. – P. 570–575.
Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme / K. Maier-Hauff, F. Ulrich, D. Nestler [et al.] // Journal of Neuro-Oncology. – 2011. – Vol. 103, N 2. – P. 317– 324.
Dutz S. Magnetic nanoparticle heating and heat transfer on a microscale: Basic principles, realities and physical limitations of hyperthermia for tumour therapy / S. Dutz, R. Hergt // International Journal of Hyperthermia. – 2013. – Vol. 29, N 8. – P. 790–800.
Magnetic properties and antitumor effect of nanocomplexes of iron oxide and doxorubicin / V. Orel, A. Shevchenko, A. Romanov [et al.] // Nanomedicine: Nanotechnology, Biology and Medicine. – 2015. – Vol. 11. – P. 47–55.
Imaging of Guerin carcinoma during magnetic nanotherapy / V. Orel, T. Mitrelias, M. Tselepi [et al.] // Journal of Nanopharmaceutics and Drug Delivery. – 2014. – Vol. 2, N 1. – P. 58–68.
Магнітна тераностика карциноми легені Льюїс комплексом гадопентетату димеглуміну з доксорубіцином / В. Е. Орел, О. Ю. Рихальський, Т. С. Головко [та ін.] // Доповіді Національної академії наук України. – 2016. – № 9. – С. 134–142.
Magnetic resonance nanotheranostics of Guerin’s carcinoma / V. E. Orel, T. Mitrelias, M. Tselepi [et al.] // IFMBE Proceedings. – Toronto, Canada : Springerlink, 2015. – Vol. 51. – P. 903–906.
