ОСОБЛИВОСТІ КЛІНІЧНОГО ПЕРЕБІГУ НОВОГО ВАРІАНТА COVID-19 – XBB.1.5

Автор(и)

  • Н. О. Яковенко
  • О. В. Чернишов

DOI:

https://doi.org/10.32782/2226-2008-2023-2-19

Ключові слова:

COVID-19, штам XBB.1.5, клінічний перебіг

Анотація

Наприкінці 2022 року з’явився новий штам SARS-CoV-2, що «викликає занепокоєння» – XBB.1.5 – “Kraken”. На відміну від попередніх штамів, він має багато суттєвих мутацій, що дозволяють йому легше оминати імунну систему людини, він має сильнішу здатність зв’язуватися з рецепторами господаря, що робить його дуже заразним. “Kraken” має не важчий перебіг, ніж інші варіанти COVID-19, за даними CDC, він становить низький ризик для здоров’я населення. В клінічній картині переважають «простудні симптоми», лихоманка при цьому відходить на другий план. Інструменти для боротьби з XBB.1.5 залишаються тими ж самими, що і на первинних етапах пандемії. Вакцинація, противірусні препарати та нефармацевтичні заходи є досить ефективними, особливо для запобігання важкого перебігу, госпіталізації та смерті.

Стаття розміщена в Інституціональному репозиторії Одеського національного медичного університету http://journal.odmu.edu.ua/?p=7611

Посилання

Tesini BL. COVID-19. Medychnyy oglyad 2022 [cited 2022 March]. (In Ukrainian). Available from: https://www.msdmanuals.com/uk/professional/infectious-diseases/covid-19/covid-19

Centers for Disease Control. Risk for COVID-19 Infection, Hospitalization, and Death. 2022 [cited 2022 Aug 11]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/your-health/understanding-risk.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Fneed-extra-precautions%2Findex.html.

Centers for Disease Control. Symptoms of COVID-19. 2022 [cited 2022 Oct. 26]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html.

World Health Organization. Tracking SARS-CoV-2 variants. 2023 [cited 2023 March 30]. Available from: https://www.who.int/activities/tracking-SARS-CoV-2-variants.

Catherman С. COVID hospitalizations rise 33% in Central Florida amid new variant, foreign spread. Orlando Sentinel. 2023 [cited 2023 Jan 09]. Available from: https://www.sun-sentinel.com/coronavirus/os-ne-print-florida-coronavirus-fridayjanuary-6-china-impact-20230109-wjc32no6vzg7rlfsd2byvjj4ji-story.html.

Karmakar S. Kraken Variant: 9 Distinct Symptoms And Other Things You Need To Know About XBB.1.5. 2023 [cited 2023 Jan 18]. Available from: https://www.thehealthsite.com/news/kraken-variant-9-distinct-symptoms-and-other-thingsyou-need-to-know-about-xbb-1-5-945097/.

World Health Organization. COVID-19: variants. 2022 [cited 2022 March 2]. Available from: https://www.who.int/westernpacific/emergencies/covid-19/information/covid-19-variants.

World Health Organization. WHO announces simple, easy-to-say labels for SARS-CoV-2 Variants of Interest and Concern. 2021 [cited 2021 May 31]. Available from: https://www.who.int/news/item/31-05-2021-who-announces-simple-easy-tosay-labels-for-sars-cov-2-variants-of-interest-and-concern.

Goodman CK. New COVID variant XBB.1.5 is fueling cases in Florida. Here’s why you’re at risk, and what to do about it. South Florida Sun Sentinel. 2023 [cited 2023 Jan 11]. Available from: https://www.sun-sentinel.com/health/fl-ne-high-riskfor-covid-in-florida-20230111-uoe54xmmgfdwri7a2p4yujh5u4-story.html.

Karmakar S. Omicron XBB.1.5 Variant More Likely To Infect Fully Vaccinated And People Who Have Had COVID-19: Warn Experts. 2023 [cited 2023 Jan 18]. Available from: https://www.thehealthsite.com/news/omicron-xbb-1-5-variant-more-likely-to-infect-fully-vaccinated-and-people-who-have-had-covid-19-warnexperts-945080/.

Rosen A. What you need to know about XBB.1.5, Omicron’s latest variant. Johns Hopkins Coronavirus Resource Center. 2023 [cited 2023 Jan 09]. Available from: https://coronavirus.jhu.edu/from-our-experts/what-you-need-to-know-aboutxbb-1-5-omicron-s-latest-variant.

Schofield C. Orthrus CH.1.1: new COVID variant spreading in UK alongside Kraken as UKHSA issues warning. 2023 [cited 2023 Jan 23]. Available from: https://www.nationalworld.com/health/coronavirus/orthrus-ch11-covid-variant-uk-krakenukhsa-3990197.

Schofield C. Kraken COVID symptoms: doctor shares top signs affecting people so far – and the ones that are less likely. 2023 [cited 2023 Jan 13]. Available from: https://www.nationalworld.com/health/coronavirus/kraken-covid-symptomsdoctor-top-signs-3991959.

European Centre for Disease Prevention and Control. Implications for the EU/EEA of the spread of the SARS-CoV-2 Omicron XBB.1.5 sub-lineage. Threat assessment brief. 2023 [cited 2023 Jan 18]. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/TAB- Implications%20for%20the%20EU-EEA%20of%20the%20spread%20of%20the%20SARS-CoV-2%20Omicron%20XBB.1.5%20sub-lineage.pdf.

Rosen A. What you need to know about XBB.1.5, Omicron’s latest variant. Johns Hopkins Coronavirus Resource Center. 2023 [cited 2023 Jan 09]. Available from: https://coronavirus.jhu.edu/from-our-experts/what-you-need-to-know-about-xbb-1-5-omicron-s-latest-variant.

Sugano A, Kataguchi H, Ohta M, Someya Y. SARS-CoV-2 Omicron XBB.1.5 may be a variant that spreads more widely and faster than other variants. 2023 [cited 2023 Jan 31]. Available from: https://doi.org/10.1101/2023.01.18.524660.

Public Health Center of the Ministers of Health of Ukraine. The reference laboratory of the Public Health Center confirmed a case of mutation of the Omicron XBB.1.5 variant. 2023 [cited 2023 Jan 24]. (In Ukrainian). Available from: https://www.phc.org.ua/news/referens-laboratoriya-centru-gromadskogo-zdorovya-pidtverdila-vipadok-mutacii-variantu-omicron.

Public Health Center of the Ministers of Health of Ukraine. The Omicron XBB.1.5 variant is confirmed in 4 areas: sequencing results of the reference laboratory of the PHC. 2023 [cited 2023 Febr 22]. (In Ukrainian). Available from: https://www.phc.org.ua/news/variant-omicron-xbb15-pidtverdzheno-v-4-oblastyakh-rezultati-sekvenuvannya-referens.

Prater E. Kraken is dominating U.S. COVID cases, the CDC predicts, as deaths jump 44% in one week. 2023 [cited 2023 Jan 13]. Available from: https://fortune.com/well/2023/01/13/kraken-xbb15-omicron-covid-variant-dominant-in-us-unitedstates-cdc-deaths-rise-new-york/.

European Centre for Disease Prevention and Control. ECDC assesses risk to the EU/EEA associated with Omicron XBB.1.5 sub-lineage. 2023 [cited 2023 Jan 13]. Available from: https://www.ecdc.europa.eu/en/news-events/covid-19-implicationsspread-omicron-xbb15.

European Centre for Disease Prevention and Control. Threat Assessment Brief: Implications for the EU/EEA of the spread of the SARS-CoV-2 Omicron XBB.1.5 sub-lineage. 2023 [cited 2023 Jan 13]. Available from: https://www.ecdc.europa.eu/en/publications-data/covid-19-threat-assessment-brief-implications-spread-omicron-xbb.

ZOE Health Study. What are the most common COVID symptoms? 2022 [cited 2022 Dec 13]. Available from: https://health-study.joinzoe.com/blog/covid-new-top-10-covid-symptoms.

Joi P. Here’s what we know about the new Omicron variant XBB.1.5. VaccinesWork. 2023 [cited 2023 Jan 6]. Available from: https://www.gavi.org/vaccineswork/heres-what-we-know-about-new-omicron-variant-xbb15.

Expert reaction to the Omicron XBB.1.5 COVID variant. Science media centre. 2023 [cited 2023 Jan 4]. Available from: https://www.sciencemediacentre.org/expert-reaction-to-the-omicron-xbb-1-5-covid-variant/.

Cosdon N. Omicron XBB.1.5: Heightened Transmissibility, Infectivity, and Immune Resistance. Contagion live. 2023 [cited 2023 Mar 16]. Available from: https://www.contagionlive.com/view/omicron-xbb-1-5-heightened-transmissibility-infectivity-and-immune-resistance.

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Опубліковано

2023-09-19

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