OUTCOMES OF USING XENOGENEIC MATERIALS FOR GINGIVAL RECESSION TREATMENT: ANALYSIS OF SYSTEMATIC REVIEWS AND META-ANALYTICAL STUDIES’ DATA
DOI:
https://doi.org/10.32782/2226-2008-2023-2-16Keywords:
gingival recession, xenogeneic collagen matrix, systematic reviewsAbstract
There are significant number of systematic reviews and meta-analyses dedicated to the evaluation of the effectiveness of various graft types and surgical techniques used for the treatment of gingival recession. However, only few of them are dedicated to the analysis of using specifically xenogenic materials for the gingival recession treatment. The aim of the study. To analyze the data of systematic reviews and meta-analytical studies regarding clinical effectiveness of xenogeneic materials use for gingival recession treatment. Materials and methods. The initial search for systematic reviews and meta-analytical studies was carried out within the PubMed (NCBI) (https://www.ncbi.nlm.nih.gov/pubmed/) database by the keywords “recession” and “xenogeneic” while also using the filters “Systematic review” and “Meta-analysis”. Additional search for relevant publications was provided via Google Scholar (https://scholar.google.com/) engine while using similar keywords and advanced search capabilities. Results. Overall 12 systematic reviews and meta-analytical studies were analyzed. In most of the systematic reviews and meta-analyzes data regarding clinical benefits of using xenogeneic materials in combination with surgical techniques for the gingival recession treatment was characterized by the high degree of heterogeneity. The additional use of xenogeneic collagen matrix in combination with coronary-advanced flap characterized with the better clinical outcomes for recession treatment compare to the results obtained with coronally-advanced flap separately, while the objective clinical benefits of such approach vary. Conclusions. Despite the registered data heterogeneity extracted from systematic reviews, it was established that xenogeneic collagen matrix may be used as perspective material in combination with surgical techniques for gingival recession treatment, and such approach may be interpreted as an alternative in the condition of limited possibilities for using connective tissue graft, acellular dermal matrix and enamel matrix derivatives with the analogical objective.
The article is available at the Institutional Repository of Odesa National Medical University http://journal.odmu.edu.ua/?p=7605&lang=en
References
Di Gianfilippo R, Wang IC, Steigmann L, Velasquez D, Wang HL, Chan HL. Efficacy of microsurgery and comparison to macrosurgery for gingival recession treatment: a systematic review with meta-analysis. Clinical Oral Investigations. 2021 Jul;25(7):4269–80. doi: 10.1007/s00784-021-03954-0.
Cao Q, Lu R, Chen J, Pan H, Feng H, Liu B, et al. Treatment of gingival recession with microinvasive surgical technology. Journal of Nanomaterials. 2021 Apr 26;2021:1–6. doi: 10.1155/2021/9972879.
Krasnokutskyy O, Goncharuk-Khomyn M, Rusyn V, Tukalo I, Myhal O, Pal Y. Gingival Recession Treatment with the Use of Xenogeneic Matrix: Optimization of Patient-Centered Outcomes by the Digital Soft Tissue Design. Pesquisa Brasileira em Odontopediatria e Clínica Integrada. 2022;22:e220098. doi: 10.1590/pboci.2022.063.
Goyal L, Chawla K. Efficacy of microsurgery in treatment of localized or multiple gingival recession: A systematic review. Journal of Oral Biology and Craniofacial Research. 2021 Apr 1;11(2):237-44. doi: 10.1016/j.jobcr.2021.02.004
Ryder MI, Armitage GC. Minimally invasive periodontal therapy for general practitioners. Periodontology 2000. 2016 Jun;71(1):7–9. doi: 10.1111/prd.12132.
Rotundo R, Genzano L, Patel D, D'Aiuto F, Nieri M. Adjunctive benefit of a xenogenic collagen matrix associated with coronally advanced flap for the treatment of multiple gingival recessions: A superiority, assessor‐blind, randomized clinical trial. Journal of clinical periodontology. 2019 Oct;46(10):1013-23. doi: 10.1111/jcpe.13168.
Huang JP, Liu JM, Wu YM, Dai A, Hu HJ, He FM, et al. Clinical evaluation of xenogeneic collagen matrix versus free gingival grafts for keratinized mucosa augmentation around dental implants: A randomized controlled clinical trial. Journal of Clinical Periodontology. 2021 Oct;48(10):1293–301. doi: 10.1111/jcpe.13518.
AlSarhan MA, Al Jasser R, Tarish MA, AlHuzaimi AI, Alzoman H. Xenogeneic collagen matrix versus connective tissue graft for the treatment of multiple gingival recessions: A systematic review and meta‐analysis. Clinical and Experimental Dental Research. 2019 Oct;5(5):566-79. doi: 10.1002/cre2.210.
Cardaropoli D, Tamagnone L, Roffredo A, Gaveglio L. Treatment of gingival recession defects using coronally advanced flap with a porcine collagen matrix compared to coronally advanced flap with connective tissue graft: a randomized controlled clinical trial. Journal of periodontology. 2012 Mar;83(3):321-8. doi: 10.1902/jop.2011.110215.
Atieh MA, Alsabeeha N, Tawse‐Smith A, Payne AG. Xenogeneic collagen matrix for periodontal plastic surgery procedures: A systematic review and meta‐analysis. Journal of periodontal research. 2016 Aug;51(4):438-52. doi: 10.1111/jre.12333
Amine K, El Amrani Y, Chemlali S, Kissa J. Alternatives to connective tissue graft in the treatment of localized gingival recessions: A systematic review. Journal of stomatology, oral and maxillofacial surgery. 2018 Feb 1;119(1):25-32. doi: 10.1016/j.jormas.2017.09.005.
Chambrone L, Ortega MA, Sukekava F, Rotundo R, Kalemaj Z, Buti J, et al. Root coverage procedures for treating single and multiple recession‐type defects: An updated Cochrane systematic review. Journal of periodontology. 2019 Dec;90(12):1399-422. doi: 10.1002/JPER.19-0079.
Huang JP, Liu JM, Wu YM, Chen LL, Ding PH. Efficacy of xenogeneic collagen matrix in the treatment of gingival recessions: A systematic review and meta‐analysis. Oral diseases. 2019 May;25(4):996-1008. doi: 10.1111/odi.12949.
Moraschini V, de Almeida DC, Sartoretto S, Bailly Guimarães H, Chaves Cavalcante I, Diuana Calasans-Maia M. Clinical efficacy of xenogeneic collagen matrix in the treatment of gingival recession: a systematic review and meta-analysis. Acta Odontologica Scandinavica. 2019 Aug 18;77(6):457-67. doi: 10.1080/00016357.2019.1588372.
Moraschini V, Calasans-Maia MD, Dias AT, de Carvalho Formiga M, Sartoretto SC, Sculean A, Shibli JA. Effectiveness of connective tissue graft substitutes for the treatment of gingival recessions compared with coronally advanced flap: a network meta-analysis. Clinical oral investigations. 2020 Oct;24:3395-406. doi: 10.1007/s00784-020-03547-3.
de Carvalho Formiga M, Nagasawa MA, Moraschini V, Ata-Ali J, Sculean A, Shibli JA. Clinical efficacy of xenogeneic and allogeneic 3D matrix in the management of gingival recession: a systematic review and meta-analysis. Clinical oral investigations. 2020 Jul;24:2229-45. doi: 10.1007/s00784-020-03370-w.
Bhatia A, Yadav VS, Tewari N, Kumar A, Sharma RK. Efficacy of modified coronally advanced flap in the treatment of multiple adjacent gingival recessions: A systematic review and meta-analysis. Acta Odontologica Scandinavica. 2021 Nov 17;79(8):562-72. doi: 10.1080/00016357.2021.1908594.
Barootchi S, Tavelli L, Zucchelli G, Giannobile WV, Wang HL. Gingival phenotype modification therapies on natural teeth: A network meta‐analysis. Journal of Periodontology. 2020 Nov;91(11):1386-99. doi: 10.1002/JPER.19-0715.
Dai A, Huang JP, Ding PH, Chen LL. Long‐term stability of root coverage procedures for single gingival recessions: A systematic review and meta‐analysis. Journal of Clinical Periodontology. 2019 May;46(5):572-85. doi: 10.1111/jcpe.13106.
