THE PROCEDURE OF THERMAL IMAGING CONTROL OF THE TEMPERATURE FIELDS ON THE SKIN DURING CRYOABLATION
DOI:
https://doi.org/10.32782/2226-2008-2023-4-17Keywords:
infrared thermography, skin, cryosurgery, dynamics of temperature fieldsAbstract
Introduction. In the treatment of malignant skin diseases using the cryosurgical method, the radicality of cryoablation is primarily used, which ensures the patient’s recovery and reduces the likelihood of disease recurrence. One of the non-invasive remote methods of intraoperative control of the temperature field is infrared thermography, which records the dynamics of thermal fields that reflect the distribution and activity of internal processes in tissues. The work aims to develop a thermal imaging technique for monitoring the dynamics of thermal fields on the skin during short-term low-temperature exposure with a quasi-point cryoapplicator. Materials and methods. The technique is based on remote measurement of the intensity of temperature fields on the surface of the skin, finding abnormal areas of these fields and quantitative assessment of the parameters of abnormal areas and their dynamics. Cryodestruction of the skin and underlying tissues was carried out with a quasi-point cryoapplicator cooled by liquid nitrogen, and thermal imaging examination was carried out with an original infrared camera, specially designed for studies of the dynamics of low-temperature thermal fields. Results and discussion. Based on the results of thermal imaging studies, a method of monitoring the dynamics of temperature fields on the skin during low-temperature exposure with a quasi-point cryoapplicator has been developed. The work describes the requirements for thermal imaging inspection conditions, provides the necessary technical parameters of the equipment, and also presents a detailed step-by-step description of the measurements and quantitative analysis of the obtained results. Conclusions. The methodology can become the basis for developing an appropriate “clinical protocol”, the implementation of which in clinical practice will contribute to the improvement of the quality of treatment of patients by increasing the accuracy of diagnosis, prevention of complications and relapses.
References
Abramovits W, Graham G, Har-Shai Ya, Strumia R. Dermatological cryosurgery and cryotherapy. London: Springer. 2016. 758 p. DOI: https://doi.org/10.1007/978-1-4471-6765-5
Chyzh MO, Belochkina IV, Hladkykh FV. Cryosurgery and physical medicine in treatment of cancer. Ukrainian journal of radiology and oncology. 2021; 29(2): 127–149. Available from: https://ukroj.com/index.php/journal/article/view/93.
Zimmerman EE, Crawford P. Cutaneous cryosurgery. Am. Fam. Physician, 86 (2012) 1118–1124. Available from: https://www.aafp.org/afp/2012/1215/p1118.html.
Chizh NA. Endoscopic Cryosurgery. Probl Cryobiol Cryomed 2017; 27(1): 03–18. DOI: https://doi.org/10.15407/cryo27.01.003.
Pasquali P. Cryosurgery. Berlin, Heidelberg: Springer-Verlag; 2015. 315 p.
Hoffmann NE, Bischof JC. Cryosurgery of normal and tumor tissue in the dorsal skin flap chamber: Part I-thermal response, J Biomech Eng. 2001; 123: 301–9. DOI: https://doi.org/10.1115/1.1385838.
Lutz NW, Bernard V. Contactless thermometry by MRI and MRS: advanced methods for thermotherapy and biomaterials. iScience. 2020; 23: e101561, DOI: https://doi.org/10.1016/j.isci.2020.101561.
Overduin CG, Fütterer JJ, Scheenen TWJ. 3D MR thermometry of frozen tissue: feasibility and accuracy during cryoablation at 3T. J. Magn. Reson. Imag. 2016; 44: 1572–1579. DOI: https://doi.org/10.1002/jmri.25301.
Diakides NA, Bronzino JD. Medical infrared imaging. New York: CRC Press; 2007. 448 p.
Kiporenko PV, Gordiyenko EYu, Fomenko YuV, Shustakova GV. The procedure for measurement of the human temperature field dynamics. Ukrainian Metrological Journal. 2018; 3: 62–6. DOI: https://doi.org/10.24027/2306-7039.3.2018.153131.
Glushchuk NI, Gordiyenko EYu, Fomenko YuV, Shustakova GV, Miroshnichenko LG, Kolotilov NN. The Results of the Study of Human Anomalos Thermal Fields under Irradiation. Sci Innov. 2017; 13(2): 43–52. DOI: https://doi.org/10.15407/scine13.02.043.
Kovalov GO, Gordiyenko EYu, Fomenko YuV. Shustakova GV, Kiporenko PV, Olefirenko OO. Dynamics of freezing and warming of soft tissues with short-term effect on skin with cryoapplicator. Probl Cryobiol Cryomed. 2020; 30(4): 359–68. DOI: https://doi.org/10.15407/cryo30.04.359.
Kovalov GO, Shustakova GV, Gordiyenko EYu, Fomenko YuV, Glushchuk MI. Infrared thermal imaging controls freezing and warming in skin cryoablation. Cryobiology. 2021; 103: 32–8. DOI: https://doi.org/10.1016/j.cryobiol.2021.09.014.
Вироби медичні електричні (1) Додаткові вимоги щодо безпеки та основних робочих характеристик термографів для скринінгу фебрильної температури тіла людини. ДСТУ EN 80601-2-59:2015. 2015. Available from: https://www.dls.gov.ua/wp-content/uploads/2020/02/16088-dn_20200120_117_dod_3.pdf.
Cohen EEW, Ahmed O, Kocherginsky M, Shustakova G, Kistner-Griffin E, Salama JK et al. Study of functional infrared imaging for early detection of mucositis in locally advanced head and neck cancer treated with chemoradiotherapy. Оral oncol. 2013; 49 (10): 1025–1031. DOI: https://doi.org/10.1016/j.oraloncology.2013.07.009.
