MEDICAL AND SOCIAL ASPECTS OF ATOPIC DERMATITIS IN CHILDREN

Authors

  • Т. V. Stoyeva
  • О. V. Тіtkova
  • О. V. Reshitilo
  • М. V. Fedin
  • К. V. Оstapchuk
  • В. І. Zamyshlyak

DOI:

https://doi.org/10.32782/2226-2008-2023-2-5

Keywords:

children, atopic dermatitis, quality of life

Abstract

The data obtained in the work indicate the importance of improving the existing tools for assessing the quality of life, especially for infants. A detailed study of the medico-social aspects of atopic dermatitis in children, taking into account gender and age characteristics, allows to improve diagnostic possibilities, optimize treatment and prevention tactics, in particular thanks to effective forecasting of the course of the disease, and dynamic analysis of quality of life indicators is an important tool for determining the effectiveness of therapeutic schemes. The presence of atopic dermatitis disrupts the usual way of life, negatively affects the harmonious and spiritual development of the child. The prognostic value of the most significant factors affecting the quality of life (itching of the skin and sleep disturbances) was revealed: with a value of ≥ 2.0 points for each sign, the sensitivity and specificity indicators are 91.5% (Se), 50.0% (Sp). Medico-social factors in atopic dermatitis were analyzed, taking into account gender characteristics and revealed a higher influence of clinical indicators – itching (p = 0.017), sleep disturbance (p < 0.001), level of eosinophils (p = 0.001) and Ig E (p = 0.002) in male patients. Psychosocial problems in children with atopic dermatitis are caused by the impact of the disease on social relations with peers (71.2 ± 5.9%), significant limitations in patients’ “leisure time” (72.9 ± 5.8%), “psychological” (83.3±4.9%) and “physical” (72.3±5.8%) well-being.

The article is available at the Institutional Repository of Odesa National Medical University http://journal.odmu.edu.ua/?p=7573&lang=en

References

Li A, Zhang M, Yang Y, Zhang J, Xie X, Li X, Zhang H. Patient-reported outcome (PRO) instruments for disease severity and quality of life in patients with atopic dermatitis: a systematic review of English and Chinese literature. Ann Transl Med. 2022 Aug; 10(16):906. doi: 10.21037/atm-22-3164. PMID: 36111032; PMCID: PMC9469158.

Reshetilo OV. Clinical and pathogenetic models and differential therapy for atopic dermatitis in children: dissertation on the health of the scientific level of a Candidate of Medical Sciences. 2020.

Na CH, Chung J, Simpson EL. Quality of Life and Disease Impact of Atopic Dermatitis and Psoriasis on Children and Their Families. Children (Basel). 2019 Dec 2; 6(12): 133. doi: 10.3390/children6120133. PMID: 31810362; PMCID: PMC6955769.

Allergic Comorbidity of Asthma or Wheezing, Allergic Rhinitis, and Eczema: Result From 333 029 Allergic Children in Shanghai, China / Heyu Ji, Yi Hu, Ting Zhang et al. American Journal of Rhinology & Allergy. 2019. Vol. 34, iss. 2. P. 189–195. Available from: https://doi.org/10.1177/1945892419883238.

Sur M, Boca AN, Ilies RF, Floca E, Tataru A and Sur L: Correlation between quality of life and disease severity of pediatric patients with atopic dermatitis. Exp Ther Med. 2020; 20: 189.

Stoieva TV, Reshetilo LV, Titkova EV. Effectiveness of the hypoxalic diet in treatment of children with atopic dermatitis. Pediatrics. Eastern Europe. 2018. V. 6, No. 3. 421–428. Available from: https://www.onmedu.edu.ua/xmlui/bitstream/handle/123456789/5634/Stoieva.pdf?sequence=1&isAllowed=y.

Dreno B, Amici JM, Demessant-Flavigny AL, Wright C, Taieb C, Desai SR, Alexis A. The Impact of Acne, Atopic Dermatitis, Skin Toxicities and Scars on Quality of Life and the Importance of a Holistic Treatment Approach. Clin Cosmet Investig Dermatol. 2021 Jun 14; 14: 623–632. doi: 10.2147/CCID.S315846. PMID: 34163201; PMCID: PMC8213955.

Johansson EK, Brenneche A, Trangbaek D, Stelmaszuk MN, Freilich J, & Anderson CD. Treatment Patterns among Patients with Atopic Dermatitis in Secondary Care: A National, Observational, Non-interventional, Retrospective Study in Sweden. Acta Dermato-Venereologica, 2022. 102, adv00774. Available from: https://doi.org/10.2340/actadv.v102.1986.

Stoieva T, Titkova O, Reshetilo L, & Yurchenko Y. Medico-social features of atopic dermatitis in children of different ages. InterConf, 2021; 50. Available from: https://ojs.ukrlogos.in.ua/index.php/interconf/article/view/11447.

Published

2023-09-19

Issue

Section

CLINICAL PRACTICE